Summary: This report is based on seven papers for the Global Burden of Disease Study 2010 published in The Lancet (December 13, 2010; 380). This publication summarizes the global GBD 2010 findings as well as the regional findings for Europe and Central Asia (ECA). It also explores intraregional differences in diseases, injuries, and risk factors. Main findings for Europe and Central Asia include the following: 1) ECA have made significant progress in reducing mortality and prolonging life since 1970; 2) over the last 20 years, the region has succeeded in decreasing premature death and disability from most communicable, newborn, nutritional, and maternal causes with the exception of HIV/AIDS; 3) between 1990 and 2010, disease burden from many non-communicable causes increased, especially ischemic heart disease, cirrhosis, diabetes, and musculoskeletal disorders including low back pain and neck pain; 4) the region has seen a sharp increase in injuries associated with interpersonal violence and self-harm, but there was a decline in injuries resulting from fire, drowning, and poisonings; 5) in ECA the leading causes of disability in the region largely mirrored global trends. Mental disorders such as depression and anxiety as well as low back pain, neck pain, and other musculoskeletal disorders were dominant causes of disability; and 6) dietary risks, high blood pressure, alcohol use, smoking, high body mass index, and physical inactivity were leading risk factors for premature death and disability in ECA.
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